SPONSORED ADVERTISING CONTENT
2025's Top 5 Dry Eye Supplements
With so many dry eye supplements promising relief, it’s hard to know what really works. Here’s the truth about what helps, what doesn’t, and the top 5 we recommend.
Advertiser Disclosure
Blink Twice If You Need Help
A 60% drop in blink rate. That’s what happens when you're locked onto a screen for hours—and it’s one of the fastest ways to dry your eyes out, according to eye health experts. That’s a problem, because blinking isn’t just a reflex—it’s how your eyes stay protected, lubricated, and nourished. Fewer blinks means more dryness, more discomfort, and more strain. Over 6 million Americans report dry eye symptoms without ever receiving a diagnosis, and for adults over 65, the issue is frequently downplayed or misunderstood.
If you’ve felt the stinging, blurring, or everyday irritation that comes from staring too long without blinking, you’re not imagining it. And while screen breaks, hydration, and blink exercises can help, they don’t address the underlying biological wear and tear on your eyes. That kind of damage could be an early warning sign of deeper, aging decline.
That’s where targeted nutrition comes in. A high-quality vision supplement can support tear film stability, protect against oxidative stress, and help reduce the irritation that contributes to dryness—benefits you simply can’t get from surface-level solutions alone. But not all supplements are created equal. At Smarter Reviews, we analyze the science, formulas, and clinical backing behind today’s leading eye health products so you can choose one that actually works.
The Hidden Costs of Screen-Stressed Eyes
Healthy vision is about more than just seeing clearly—it’s about protecting your independence and staying fully engaged with life. But with blue light, screen time, and environmental stressors quietly accelerating age-related eye changes, dryness is often the first warning sign.
The real challenge? Knowing which solution actually works. Choosing the right support now can make all the difference later. The right nutrients can help ease dryness, defend against daily stressors, and preserve healthy function, so you can stop worrying about screen time and stay focused on what matters most.
Dry Eye Health Supplements Help Support:
Hydration and Tear Film Stability for Dry Eye Relief from Screen Use
Defense Against Blue Light Damage
Comfort from Typical Irritation and Eye Fatigue
Antioxidant Protection for Ocular Cells
Nutritional Support with Vitamin A and Vitamin E for Dry Eyes
Decreased Risk of Common Eye Strain Symptoms like Hazy, Blurred, or Double Vision
Vitamin A For Dry Eyes
Vitamin A plays a vital role in keeping the eye’s surface tissues—especially the cornea and conjunctiva—hydrated and healthy. Deficiencies can lead to dryness, irritation, and even long-term damage to tear-producing glands. Inside-out support with bioavailable forms of vitamin A helps reinforce the eye's natural moisture barrier and improve tear film quality over time.
How Vitamin A Changes Your Supplement
Supplements With Vitamin A
♦ Strong support for dark adaptation and low-light vision
♦ Helps prevent dryness, irritation, and oxidative stress
♦ Directly supports retina’s ability to process light
♦ Must manage dose carefully, especially with retinyl forms
♦ Contains Vitamin A, best in beta-carotene form (safe + effective)
Supplements Without Vitamin A
♦ May lack core functional support for rhodopsin regeneration
♦ Could increase risk of dryness or insufficient surface protection
♦ Missing a key biochemical link in retinal function
♦ Safer in some populations (e.g., smokers or those at risk of hypervitaminosis A)
♦ May rely on indirect benefits from lutein/zeaxanthin or omega-3s
Backed by Research: AREDS 2 + CARMIS Clinical Studies
The AREDS 2 (Age-Related Eye Disease Study 2) and CARMIS (Carotenoids and Retinopathy in Macular degeneration Italian Study) clinical trials set the gold standard for vision support, showing that antioxidants like lutein and zeaxanthin can slow age-related macular issues and support long-term eye function.
While these trials focused on macular health, newer research shows many of the same ingredients—like astaxanthin—may also support common dry eye relief by reducing oxidative stress and promoting tear production.
Some supplements stick to ingredients from the original AREDS 2 formula, delivering foundational nutrients at clinical doses. Others go further, adding next-generation compounds that target not just early macular changes, but also hydration, circulation, and digital eye strain. Knowing the difference between basic and comprehensive formulas can help you choose the right solution for your eyes.
What to Look For in a Dry Eye Health Supplement
Clinically Studied Formulas
Look for supplements that use ingredients backed by robust clinical research, especially those shown to support tear stability and eye hydration. Effective doses—like 10mg of lutein and 2mg of zeaxanthin from the AREDS2 trial—are key for not only macular health but also reducing oxidative stress that contributes to dry eye.
Protection From Blue Light
XanMax® (lutein and zeaxanthin) filters blue light to ease strain and support macular health. Screen use can cut blink rate by up to 60%, leading to dryness. These nutrients may help maintain natural blinking and support tear film stability.
More Than Just Beta-Carotene
Many products rely solely on beta-carotene, which may not be ideal for everyone. Advanced formulas include full-spectrum mixed carotenes, such as those derived from virgin palm oil, which can be converted into vitamin A—supporting low-light vision, retinal age spots, and overall eye surface hydration.
Macular & Retinal Circulation Support
Astaxanthin is a powerful carotenoid that crosses the blood-retina barrier. It's clinically shown to support ciliary muscle function (important for focusing), improve visual function and visual acuity, and enhance hydration—making it a valuable addition for those experiencing dry eye symptoms and those with age-related macular changes.
Formulated for Daily Use
Convenience matters. A well-rounded supplement should deliver comprehensive support in a simple, once-daily formula—helping maintain visual clarity and comfort with minimal disruption to your routine.
What to Avoid in an Eye Health Supplement
Generic Carotenes
Low-quality supplements often rely on synthetic or generic beta-carotene. These forms may lack the diversity, balance, and effectiveness of naturally sourced mixed carotenes that more closely resemble the nutrient profile found in whole foods.
Unverified Claims
Some products market themselves as “AREDS2-inspired” but fall short when it comes to actual ingredient quality or dosage. Always check the supplement facts panel to ensure the product contains clinically supported amounts of lutein, zeaxanthin, and other critical nutrients.
Incomplete Formulas
Effective eye health requires a blend of antioxidants, carotenoids, and support compounds—not just one or two ingredients. Be cautious of formulas that omit key nutrients like astaxanthin, mixed carotenes, or those that ignore hydration, circulation, and muscle support—factors essential for everyday relief from dryness and fatigue. Many products marketed as vitamins for dry eyes or eye dryness supplements may leave out critical nutrients like astaxanthin or fail to include full-spectrum carotenoids for macular support.
Top 5 Dry Eye Supplements of 2025
Now that you understand the benefits of a vision health supplement, what to look for, and what to avoid, we’ve compiled the top five formulas offering the most complete support for long-term eye health and comfort. These rankings are based on ingredient quality, clinical backing, consumer reviews, and overall value.
1. VisionMD®
.png)
Total Ranking
9.7/10
A+
Overall Grade
PROS
- Contains EVTene™ Mixed Carotenes (1530mcg of Vitamin A per serving)
- Contains XanMax®
- Contains Lutein
- Contains Zeaxanthin
Contains Astaxanthin (Natural Source of Antioxidants)
Contains Tocopherols (Vitamin E)- Contains Lycomato® Lycopene
Includes Clinically Studied Ingredients- Promotes Healthy Tear Production
- Supports Tear Film and Overall Ocular Health
- Zero Artificial Additives or Fillers
- NSF® Contents Tested & Certified
- 90-Day Money-Back Guarantee
- 10% Discount Code for First-Time Buyers
CONS
- Only available online
- Premium pricing compared to alternatives
The Bottom Line
VisionMD® was inspired by the CARMIS and AREDS2 formulas and includes clinically studied dosages of lutein and zeaxanthins to give you the vision support you need.
This formula also contains mixed carotenes, which your body uses to produce the natural Vitamin A your eyes need. VisionMD® also includes astaxanthin and tocopherols to improve visual function and visual acuity.These help protect the cells and nutrients on the way to your eyes. These ingredients also work together to help reduce common symptoms of common dry eye, like typical irritation and discomfort.
Backed by clinical research and trusted by health professionals, VisionMD® stands out in a crowded market. 73% of users experienced healthy vision acuity and clarity, 60% experienced reduction in everyday eye fatigue and/or strain, and 44% noticed night vision support (based on a survey of over 170 participants; customers were compensated for their participation).
This product also contains no artificial fillers or additives, meaning that all of its ingredients are dedicated to strengthening your vision health.
Recognized with awards like the 2024 Eye Health Innovation Award and the 2023 Delicious Living Supplement Award, it remains a trusted choice among MDs and ODs for comprehensive vision care.VisionMD® comes with a 90-day money-back guarantee, showing us that this company stands behind its product.
With almost half a million bottles sold, VisionMD® continues to offer a trusted, results-driven solution for those seeking lasting improvements in eye health and overall visual performance.
Also, the more you stock up, the more you save and the better results you'll have. In fact, first-time buyers get an extra 10% off with discount code "First10". Just remember to use the code at checkout.
This isn’t just another supplement—it’s one of the few designed to meet the highest clinical standards and deliver real, measurable results.
*Results are based on users' personal experiences collected on this page and do not necessarily reflect typical results of using these products. Please see product website for more information.
Get an Extra 10% Off2. Blink NutriTears®

Total Ranking
9.5/10
A
Overall Grade
PROS
- Contains XanMax®
- Contains Tocopherols (Vitamin E)
- Proprietary Blend: Curcumin, Lutein, Zeaxanthin, Vitamin D
- Clinically Proven to Improve Tear Film Stability
- Developed with Eye Care and Nutritional Experts
- Promotes Healthy Tear Production
- Reduces Dry Eye Symptoms and Discomfort
- Supports Tear Film and Overall Ocular Health
CONS
- Does not contain Vitamin A
The Bottom Line
BlinkTM NutriTears® is a clinically proven dry eye supplement that targets tear production and stability through a unique, non-omega-3-based formula. Combining curcumin, lutein, zeaxanthin, and vitamin D, it delivers antioxidant and anti-inflammatory support to reduce discomfort associated with dry eyes. While it lacks omega-3s and carotenoid diversity seen in more comprehensive formulas, it stands out for those seeking a fish-free, fast-acting option. Blink NutriTears can provide noticeable relief within 2-4 weeks, making it a compelling alternative—though not as broad in scope as VisionMD®, which supports common dry eye along with full-spectrum ocular and macular health.
*Results are based on the Smarter Reviews Ranking System and do not necessarily reflect typical results from the use of these products. Please visit product websites for more information.
Learn More3. Hydroeye®

Total Ranking
8.9/10
B+
Overall Grade
PROS
- Contains Tocopherols (Vitamin E)
Omega Blend: GLA, EPA, DHA
Lutein and zeaxanthin- Clinically Tested to Support Dry Eye Comfort
Promotes Healthy Tear Production
Reduces Dry Eye Symptoms and Discomfort
Supports Tear Film and Overall Ocular Health
NSF® Contents Tested & Certified
CONS
- Only available online
- Contains Fish Oil
- Does not contain lutein
- Does not contain zeaxanthin
- Does not include a broader spectrum of carotenoids and antioxidants
Limited focus on macular and retinal health- Lacks long-term ocular circulation support
Increased capsule count per serving
The Bottom Line
HydroEye® is a clinically tested supplement that takes a multi-nutrient approach to dry eye support, combining GLA, EPA, DHA, antioxidants, and key vitamins to promote a healthy tear film and soothe the ocular surface. While it may take several weeks to experience noticeable relief, its synergistic blend is especially effective for those with inflammation-driven dryness. Compared to VisionMD®, which also targets visual clarity, macular health, and ocular hydration with a broader range of clinically studied ingredients, HydroEye focuses more narrowly on omega-based anti-inflammatory support. It’s a strong option for those looking specifically for an omega-rich formula.
*Results are based on the Smarter Reviews Ranking System and do not necessarily reflect typical results from the use of these products. Please visit product websites for more information.
4. EyePromise®

Total Ranking
8.7/10
B+
Overall Grade
PROS
- Contains Tocopherols (Vitamin E)
Soothing Ingredients: Turmeric, Green Tea Extract- Clinically Tested to Support Dry Eye Comfort
- Developed with Eye Care and Nutritional Experts
Promotes Healthy Tear Production
Reduces Dry Eye Symptoms and Discomfort- Supports Tear Film and Overall Ocular Health
- NSF® Contents Tested & Certified
CONS
- Only available online
Contains Fish Oil- Does not contain lutein
- Does not contain zeaxanthin
- Does not include a broader spectrum of carotenoids and antioxidants
- Limited focus on macular and retinal health
- Lacks long-term ocular circulation support
- Increased capsule count per serving
- Premium pricing compared to alternatives
The Bottom Line
EyePromise® EZ TearsTM is a clinically studied supplement designed to provide non-habit-forming relief from occasional dry eye symptoms. Its high-potency omega-3s, combined with natural ingredients like turmeric and green tea extract, help support healthy tear production and soothes eye discomfort . Its NSF certification adds credibility to its quality and safety. While EZ Tears is a solid option for those seeking quick relief with a well-rounded omega-based formula, it lacks some of the full-spectrum carotenoid support and advanced ocular circulation benefits found in VisionMD®, which offers broader, long-term vision and hydration benefits beyond just dry eye.
*Results are based on the Smarter Reviews Ranking System and do not necessarily reflect typical results from the use of these products. Please visit product websites for more information.
Learn More5. DE3 Omega Benefits®

Total Ranking
7.9/10
C+
Overall Grade
PROS
- Contains Tocopherols (Vitamin E)
- High-Potency Omega-3s (2,240 mg EPA & DHA)
- Clinically Proven to Improve Tear Film Stability
- Clinically Tested to Support Dry Eye Comfort
- Promotes Healthy Tear Production
- Reduces Dry Eye Symptoms and Discomfort
- Supports Tear Film and Overall Ocular Health
- NSF® Contents Tested & Certified
CONS
- Only available online
- Contains Fish Oil
- Does not contain Vitamin A
- Does not contain lutein
- Does not contain zeaxanthin
- Does not include a broader spectrum of carotenoids and antioxidants
- Limited focus on macular and retinal health
- Lacks long-term ocular circulation support
- Increased capsule count per serving
- Premium pricing compared to alternatives
The Bottom Line
PRN® DE3 Omega Benefits® is an omega-3 supplement engineered to support healthy tear production and relieve occasional eye dryness. Its ultra-purified triglyceride form of EPA and DHA offers high bioavailability, and the rigorous distillation process ensures it is free from contaminants like mercury and PCBs. Backed by clinical research and manufactured to pharmaceutical-grade standards, it's a trusted choice among eye care professionals. However, compared to VisionMD®, which combines omega-free antioxidant support with carotenoids and circulation-enhancing nutrients for broader ocular benefits, PRN DE3 is more narrowly focused on tear lipid layer support through high-dose omegas. It’s ideal for those specifically seeking a premium omega-3–driven solution.
*Results are based on the Smarter Reviews Ranking System and do not necessarily reflect typical results from the use of these products. Please visit product websites for more information.
Learn MoreDisclaimer:
Smarter Reviews is owned and operated by the same company that owns certain products featured on this website, including the products ranked number one.
In addition, we receive compensation from certain companies whose products are featured on this website when you purchase a product using the links on this website.
Go back to page
Final Takeaway
With clinically supported ingredients, a reputation for quality, and a formulation that exceeds modern vision support standards, VisionMD® by 1MD Nutrition® is one of the most comprehensive eye supplements on the market for those frustrated with the cycle of eye drops and seeking lasting relief from occasional dryness, typical irritation, digital eye strain, and signs of early macular changes.
CITATIONS
- Krinsky, N. I. (2002). Possible biologic mechanisms for a protective role of xanthophylls. The Journal of Nutrition, 132(3), 540S–542S.
- https://www.ncbi.nlm.nih.gov/pubmed/22009916
WebRN. (n.d.) Retrieved from https://www.webrn-maculardegeneration.com/lycopene.html - Lycored. (n.d.). Lyc-O-Mato® – Natural Tomato Extract. Retrieved from https://www.lycored.com/lycomato/
- ExcelVite. (n.d.). EVTene™ Mixed Carotenoids Complex. Retrieved from https://www.excelvite.com/products/evtene-mixed-carotenoids-complex/
- Carotene.org. (n.d.). Eye Health – Research on Natural Mixed Carotenes. Retrieved from https://www.carotene.org/research/eye-health/
- Examine.com. (n.d.). Vitamin A: Eye Health. Retrieved from https://examine.com/supplements/vitamin-a/
- NutriScience. (n.d.). OptiLut® Lutein + Zeaxanthin for Eye Health. Retrieved from https://nutriscienceusa.com/branded-ingredients/optilut-lutein-zeaxanthin/
- Examine.com. (n.d.). Lutein Overview. Retrieved from https://examine.com/supplements/lutein/
- Examine.com. (n.d.). Astaxanthin Overview. Retrieved from https://examine.com/supplements/astaxanthin/
- Sawaki, K., Yoshigi, H., & Takahashi, J. (2016). Oral supplementation with astaxanthin reduces eye fatigue in visual display terminal workers. Journal of Clinical Therapeutics & Medicines, 32(3), 285–291. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997915/
- National Eye Institute. (2013). Retrieved from https://www.nei.nih.gov/about/news-and-events/news/nih-study-provides-clarity-supplements-protection-against-blinding-eye-disease
- Bausch + Lomb. (n.d.). Blink™ NutriTears®: Clinically proven supplement for dry eyes. Retrieved May 23, 2025, from https://www.justblink.com/products/blink-nutritears/
- Results from a randomized, placebo-controlled clinical trial. Gioia, N., Gerson, J., & Ryan, R. (2024). A novel multi-ingredient supplement significantly improves ocular symptom severity and tear production in patients with dry eye disease: Results from a randomized, placebo-controlled clinical trial. Frontiers in Ophthalmology, 4, Article 1362113. https://doi.org/10.3389/fopht.2024.1362113
- Eltawil, A. (2025, April 24). HydroEye review: Is this supplement worth trying? Health Web Magazine. Retrieved from https://www.healthwebmagazine.com/hydroeye-review
- EyePromise. (n.d.). A nutraceutical for occasional dry eye and irritation [PDF]. Retrieved May 23, 2025, from https://explore.eyepromise.com/hubfs/New_Branding/2017%20EZ%20Tears%20Info%20Sheet.pdf
- PRN Vision Group. (n.d.). DE3 Omega Benefits® – Omega-3 for dry eye relief. Retrieved May 23, 2025, from https://prnvision.com/products/de3-omega-3-premium-dry-eye-supplements
- Asbell PA, Spiegel S. Ophthalmologist perceptions regarding treatment of moderate-to-severe dry eye: results of a physician survey. Eye Contact Lens 2010;36(1):33-8.
- Lapa I, Ferreira S, Mateus C, Rocha N, Rodrigues MA. An Exploratory Study. Int J Environ Res Public Health. 2023 Mar 4;20(5):4569. doi: 10.3390/ijerph20054569. PMID: 36901579; PMCID: PMC10001854.